Sep 14, 2012

CEREBRART - Trigeminal Neuralgia

Trigeminal Neuralgia is a disorder affecting the trigeminal nerve (the 5th cranial nerve), causing episodes of sudden, severe pain on one side of the face. Trigeminal Neuralgia has been described as among the most painful conditions known to mankind. Several theories exist to explain the possible mechanisms of Trigeminal Neuralgia. But the current theories and treatment options for Trigeminal Neuralgia are not satisfactory.

Recent data demonstrate that glial cells are involved in the development of neuropathic pain (e.g. Kimiko Kobayashi et al., Glia, Volume 60, Issue 10, pages 1529–1539, October 2012).

This CEREBRART work is an artistic interpretation of my own explanation of the possible mechanisms of Trigeminal Neuralgia.

12 comments:

  1. Neuralgia do trigêmeo provoca uma dor absolutamente inesquecível, não existe explicação.

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  2. El arte no es para entenderse es para vivirlo!

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  3. Ein Pinsel Kerne und Äuglein
    So sieht also der Schmerz allein

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  4. Gracias por tu comentario ingenioso y reflexivo! Danke für Ihre witzige und nachdenkliche Bewertung! On a serious note. Sensory neurons in the trigeminal ganglion may have no side dendrites BUT are surrounded by satellite glial cells which are obviously not just passive bystanders and may play an important role in the trigeminal ganglion integration and disintegration processes. I do not think that sensory neurons of the trigeminal ganglion are unable to communicate actively with neigbour sensory neurons via satellite glial cells. While this makes my hypothesis based on evolution of the trigeminal sensory system a little confusing for some traditionally thinking colleagues, it also makes a lot of sense as a possible explanation of the pathogenesis of trigeminal neuralgia!

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  5. trigeminal evolution, processing and pathology are much more complex than previously assumed

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  6. artist's conception of trigeminal neuralgia is interesting but the visual language of pain should be more comprehensible. so don't stop your paintings.

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  7. this experimental brain art is somewhere half way between figuration and abstraction

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  8. @Dennis: of course, this trigeminal neuralgia artistic interpretation is by no means exhaustive or all-inclusive. For sure it reflects my personal expertise and interest in intercellular communication area.

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  9. brain art = experimental brain art = cerebrart ?

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  10. Chaos And Pain Training
    http://www.muscleandstrength.com/articles/chaos-and-pain-training-what-is-it.html

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  11. where are your latest cerebrarts?

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