Trigeminal Neuralgia is a disorder affecting the trigeminal nerve (the 5th cranial nerve), causing episodes of sudden, severe pain on one side of the face. Trigeminal Neuralgia has been described as among the most painful conditions known to mankind. Several theories exist to explain the possible mechanisms of Trigeminal Neuralgia. But the current theories and treatment options for Trigeminal Neuralgia are not satisfactory.
This CEREBRART work is an artistic interpretation of my own explanation of the possible mechanisms of Trigeminal Neuralgia.
Recent data demonstrate that glial cells are involved in the development of neuropathic pain (e.g. Kimiko Kobayashi et al., Glia, Volume 60, Issue 10, pages 1529–1539, October 2012).